ULTRASOUND APPLICATION FOR TREATMENT OF ONCOLOGICAL DISEASES
Abstract
The paper proposes methods for treatment of oncological diseases while applying ultrasound as an independent method and modifier of radiation therapy.
Experimental and clinical investigations show effectiveness of ultrasound as an independent remedy against malignant tumors and its usage in combination with other anti-tumor agents. However combination effect of ultrasound and radiation on malignant neoplasms and mechanisms of radiation-sensitizing action of low-frequency ultrasonic radiation is still understudied. Influence of ultrasound input direction in malignant tumor zone has not been investigated yet and there are no rational designs of waveguides for controllable vibration impact on skin neoplasms.
About the Authors
V. T. Minchenya
Belarusian National Technical University
Belarus
Belarus
A. I. Babrouskaya
Belarusian National Technical University
D. V. Chizh
РНПЦ ОМР имени Н. Н. Александрова
References
1. Руденко, О. В. Нелинейные волны: некоторые биомедицинские приложения / О. В. Руденко // Успехи физических наук. – 2007. – Т. 177. – С. 374–383.
2. Буров, А. К. Воздействие ультраакустических колебаний высокой интенсивности на злокачественные опухоли у животных и человека / А. К. Буров, Г. Д. Андреевская // ДАН СССР. – 1956. – Т. 106. – С. 445–448.
3. Буров, В. А. Нелинейный ультразвук: разрушение микроскопических биокомплексов и нетепловое воздействие на злокачественную опухоль / В. А. Буров, Н. П. Дмит-риева, О. В. Руденко // Доклады РАН. – 2002. – Т. 383. – С. 401–404.
4. Beerlage, H. P. Alternative therapies for localized prostate cancer / H. P. Beerlage // Curr. Urrol. Rep. – 2003, Jun. – Vol. 4, Nо 3. – P. 216–220.
5. Current status of minimally invasive treatment options for localized prostate carcinoma / H. P. Beerlage [et al.] // Eur. Urol. – 2000, Jan. – Vol. 37, Nо 1. – P. 2–13.
6. Uchida, T. Minimally invasive therapy for bladder and prostate cancer / T. Uchida, M. Ohori, S. Egawa // Gan To Kagaku Ryoho. – 2001, Aug. – Vol. 28, Nо 8. – P. 1094–1098.
7. Result of transrectal focusеd ultrasound for treatment of localized prostate cancer (120 patients with PSA
8. Transcutaneous high-intensity focused ultrasound and irradiation: an organ-preserving treatment of cancer in a solitary testis / S. Madersbacher [et al.] // Eur. Urol. – 1998. – Vol. 33, Nо 2. – P. 195–201.
9. Lejbkowicz, F. Distinct sensitivity of normal and malignant cells to ultrasound in vitro / F. Lejbkowicz, S. Salzberg // Environmental Health Perspective. – 1997. – Vol. 105, Supplement 6. – P. 1575–1578.
10. Consideration on suppression of cancer cell proliferation by ultrasound exposure using sonochemical and biological measurements / A. Watanabe [et al.] // Journal of Physics : Conference Series. – 2004. – Vol. 1. – P. 210–215.
11. The antivascular action of physiotherapy ultrasound on murine tumors / A. K. W. Wood [et al.] // Ultrasound in Medicine and Biology. – 2005. – Vol. 31. – P. 1403–1410.
12. Cavitation-enhanced ultrasound thermal therapy by combined low- and high-frequency ultrasound exposure / H.-L. Liu [et al.] // Ultrasound in Medicine and Biology. – 2006. – Vol. 32. – P. 759–767.
13. A.H. Lo. Acoustic droplet vaporization: strategies for control of bubble generation and its application in minimally invasive surgery: PhD dissertation, University of Michigan, Ann Arbor, 2007. – 154 p.
14. Pulsed cavitational ultrasound therapy for controlled tissue homogenization / J. E. Parsons [et al.] // Ultrasound in Medicine and Biology. 2006. – Vol. 32. – P. 115–129.
15. Способ комбинированной терапии саркомы у крыс: пат. 13765 Респ. Беларусь, МПК (2009) A 61N 5/06, A 61Nо 7/00 / Н. В. Пономаренко, Н. И. Крутилина, В. Т. Минченя, М. В. Дроздова, Д. А. Степаненко ; заявитель Республиканский научно-практический центр онкологии и медицинской радиологии имени Н. Н. Александрова. – № a 20081024 ; заявл. 2008.07.31 ; опубл. 2010.04.30.
Review
For citations:
Minchenya V.T., Babrouskaya A.I., Chizh D.V. ULTRASOUND APPLICATION FOR TREATMENT OF ONCOLOGICAL DISEASES. Science & Technique. 2012;(1):33-39. (In Russ.)
Views:
1652
Email this article 